产品详情
简单介绍:
Anti-DUSP4 antibody (81-130) (STJ94138)
详情介绍:
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat/Monkey |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Dual specificity protein phosphatase 4 (81-130) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:20000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | DUSP4 |
Gene ID: | 1846 |
Uniprot ID: | DUS4_HUMAN |
Immunogen Region: | 81-130 |
Specificity: | MKP-2 Polyclonal Antibody detects endogenous levels of MKP-2 protein. |
Immunogen: | The antiserum was produced against synthesized peptide derived from human DUSP4. AA range:81-130 |
Post Translational Modifications | Phosphorylation in the C-terminus by ERK1/2 inhibits proteasomal degradation and stabilizes the protein. |
Function | Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2. |
Protein Name | Dual Specificity Protein Phosphatase 4 Dual Specificity Protein Phosphatase Hvh2 Mitogen-Activated Protein Kinase Phosphatase 2 Map Kinase Phosphatase 2 Mkp-2 |
Database Links | Reactome: R-HSA-112409 Reactome: R-HSA-202670 Reactome: R-HSA-5675221 |
Cellular Localisation | Nucleus |
Alternative Antibody Names | Anti-Dual Specificity Protein Phosphatase 4 antibody Anti-Dual Specificity Protein Phosphatase Hvh2 antibody Anti-Mitogen-Activated Protein Kinase Phosphatase 2 antibody Anti-Map Kinase Phosphatase 2 antibody Anti-Mkp-2 antibody Anti-DUSP4 antibody Anti-MKP2 antibody Anti-VH2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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