Mouse LOX1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) Sandwich ELISA Kit (STJE0010380) STJE0010380|产品目录|代理商|上海榴莲视频色版下载安装生物科技有限公司

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产品名称：Mouse LOX1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) Sandwich ELISA Kit (STJE0010380)
产品型号：STJE0010380
产品厂商：ST john's laboratory
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简单介绍：

Mouse LOX1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) Sandwich ELISA Kit (STJE0010380)

详情介绍：

Applications:	ELISA
Reactivity:	Mouse
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Sensitivity:	5.1pg/mL
Detection Limit:	12.5-800pg/mL
Short Description:	This LOX1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in mouse cell culture supernatant, serum and plasma (EDTA, citrate, heparin).

Storage Instruction:	Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:	4.5 hrs

Gene Symbol:	Olr1
Gene ID:	108078
Uniprot ID:	OLR1_MOUSE
Sample Type:	serum, plasma, tissue homogenates or other biological fluids.

Tissue Specificity
Post Translational Modifications	N-glycosylated.
Function	Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.
Protein Name	Oxidized Low-Density Lipoprotein Receptor 1 Ox-Ldl Receptor 1 Lectin-Like Oxidized Ldl Receptor 1 Lox-1 Lectin-Like Oxldl Receptor 1 Lectin-Type Oxidized Ldl Receptor 1 Cleaved Into - Oxidized Low-Density Lipoprotein Receptor 1 - Soluble Form
Database Links	Reactome: R-MMU-202733 Reactome: -MMU-6798695
Cellular Localisation	Cell Membrane Lipid-Anchor Single-Pass Type Ii Membrane Protein Membrane Raft Secreted A Secreted Form Also Exists Localization To Membrane Rafts Requires Palmitoylation
Alternative ELISA Names	Oxidized Low-Density Lipoprotein Receptor 1 ELISA kit Ox-Ldl Receptor 1 ELISA kit Lectin-Like Oxidized Ldl Receptor 1 ELISA kit Lox-1 ELISA kit Lectin-Like Oxldl Receptor 1 ELISA kit Lectin-Type Oxidized Ldl Receptor 1 Cleaved Into - Oxidized Low-Density Lipoprotein Receptor 1 - Soluble Form ELISA kit Olr1 ELISA kit Lox1 ELISA kit
output

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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产品名称：Mouse LOX1 (Lectin Like Oxidized Low Density Lipoprotein Receptor 1) Sandwich ELISA Kit (STJE0010380)