产品详情
简单介绍:
Anti-FN3K antibody (1-200) (STJ115680)
详情介绍:
Host: | Rabbit |
Applications: | WB |
Reactivity: | Human/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-FN3K (1-200) is suitable for use in Western Blot research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
Purification: | Affinity purification |
Dilution Range: | WB 1:500-1:2000 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | FN3K |
Gene ID: | 64122 |
Uniprot ID: | FN3K_HUMAN |
Immunogen Region: | 1-200 |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FN3K (NP_071441.1). |
Immunogen Sequence: | MEQLLRAELRTATLRAFGGP GAGCISEGRAYDTDAGPVFV KVNRRTQARQMFEGEVASLE ALRSTGLVRVPRPMKVIDLP GGGAAFVMEHLKMKSLSSQA SKLGEQMADLHLYNQKLREK LKEEENTVGRRGEGAEPQYV DKFGFHTVTCCGFIPQVNEW QDDWPTFFARHRLQAQLDLI EKDYADREARELWSRLQVKI |
Tissue Specificity | Widely expressed. Expressed in erythrocytes. |
Function | Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function. Also able to phosphorylate psicosamines and ribulosamines. |
Protein Name | Fructosamine-3-Kinase Protein-Psicosamine 3-Kinase Fn3k Protein-Ribulosamine 3-Kinase Fn3k |
Database Links | Reactome: R-HSA-163841 |
Alternative Antibody Names | Anti-Fructosamine-3-Kinase antibody Anti-Protein-Psicosamine 3-Kinase Fn3k antibody Anti-Protein-Ribulosamine 3-Kinase Fn3k antibody Anti-FN3K antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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