Anti-Folate Receptor Alpha antibody [BN3.2] (STJ16101741) STJ16101741-1|产品目录|代理商|上海榴莲视频色版下载安装生物科技有限公司

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产品名称：Anti-Folate Receptor Alpha antibody [BN3.2] (STJ16101741)
产品型号：STJ16101741-1
产品厂商：ST john's laboratory
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简单介绍：

Anti-Folate Receptor Alpha antibody [BN3.2] (STJ16101741)

详情介绍：

Host:	Mouse
Applications:	IHC-P
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description:	Mouse monoclonal antibody anti-Folate Receptor Alpha is suitable for use in Immunohistochemistry research applications.

Clonality:	Monoclonal
Clone ID:	BN3.2
Conjugation:	Unconjugated
Isotype:	IgG1
Formulation:	Tissue culture supernatant with 15mM Sodium azide
Concentration:	>=67 mg/L
Dilution Range:	IHC-P 1:100
Storage Instruction:	Store at 2-8°C upon receipt.

Gene Symbol:	FOLR1
Gene ID:	2348
Uniprot ID:	FOLR1_HUMAN
Immunogen:	Prokaryotic recombinant protein corresponding to 189 amino acids of the external domain of the folate receptor alpha molecule.

Tissue Specificity	Primarily expressed in tissues of epithelial origin. Expression is increased in malignant tissues. Expressed in kidney, lung and cerebellum. Detected in placenta and thymus epithelium.
Post Translational Modifications	The secreted form is derived from the membrane-bound form either by cleavage of the GPI anchor, or/and by proteolysis catalyzed by a metalloprotease.
Function	Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Protein Name	Folate Receptor Alpha Fr-Alpha Adult Folate-Binding Protein Fbp Folate Receptor 1 Folate Receptor - Adult Kb Cells Fbp Ovarian Tumor-Associated Antigen Mov18
Database Links	Reactome: R-HSA-204005 Reactome: R-HSA-5694530 Reactome: R-HSA-6807878
Cellular Localisation	Cell Membrane Lipid-Anchor Gpi-Anchor Apical Cell Membrane Basolateral Cell Membrane Gpi-Like-Anchor Secreted Cytoplasmic Vesicle Clathrin-Coated Vesicle Endosome Endocytosed Into Cytoplasmic Vesicles And Then Recycled To The Cell Membrane
Alternative Antibody Names	Anti-Folate Receptor Alpha antibody Anti-Fr-Alpha antibody Anti-Adult Folate-Binding Protein antibody Anti-Fbp antibody Anti-Folate Receptor 1 antibody Anti-Folate Receptor - Adult antibody Anti-Kb Cells Fbp antibody Anti-Ovarian Tumor-Associated Antigen Mov18 antibody Anti-FOLR1 antibody Anti-FOLR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance

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产品名称：Anti-Folate Receptor Alpha antibody [BN3.2] (STJ16101741)